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Research

Explore our publications and preprints advancing healthcare through rigorous AI evaluation.

Preprint
Jul 7, 2026

SycoEval-EM: Sycophancy Evaluation of Large Language Models in Simulated Clinical Encounters for Emergency Care

Large language models (LLMs) deployed in clinical decision support risk acquiescing to patient pressure for guideline-discordant care. We developed SycoEval-EM, […]

JAMA Network Open
Jun 29, 2026

Screening for Missed Opportunities for Diagnosis in the ED Using eTriggers and Large Language Models

Emergency department (ED) quality review often uses administrative electronic triggers (eTriggers), but yields on detecting missed opportunities for diagnosis (MODs) […]

Nature Medicine
Jun 26, 2026

Evaluating the robustness and readiness of large frontier models in health AI applications

Large frontier models such as GPT-5 and Gemini have demonstrated remarkable performance in a wide range of health application benchmarks. […]

Nature Biomedical Engineering
Jun 23, 2026

Large reasoning models as thinking machines for medicine

Conventional artificial intelligence has achieved remarkable feats in identifying associations and predictive patterns, yet its limitations in causal reasoning present […]

Nature
Jun 17, 2026

Towards Conversational AI for Disease Management

While large language models (LLMs) have shown promise in diagnostic dialogue1, their capabilities for effective management reasoning—including disease progression, therapeutic […]

Nature Biomedical Engineering
Jun 17, 2026

BRIDGE: benchmarking large language models for understanding real-world clinical practice texts

Large language models (LLMs) are evolving rapidly and hold great promise for medical applications, yet benchmarking on real-world clinical data […]

BMJ Digital Health & AI
Jun 12, 2026

Utilising the digital twin for disease prevention, treatment and in silico research

Much of modern healthcare remains reactive: patients present with symptoms and clinicians respond. What if, instead, we could anticipate illnesses […]

Nature Communications
Jun 12, 2026

Multimodal foundation models exploit text to make medical image predictions

Multimodal foundation models have shown compelling but conflicting performance in medical image interpretation. However, the ways in which these models […]

Science
Jun 4, 2026

A narrowing window to understand AI

As capabilities of artificial intelligence (AI) advance rapidly, human understanding of these systems is increasingly falling behind. Several trends are […]

Preprint
May 24, 2026

Teaching large language models to reason like expert diagnosticians

Differential diagnosis is an iterative process that integrates patient information with broader medical knowledge. Clinical case series such as the […]

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